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gosilico chromatography modeling software  (Cytiva Europe)


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    Cytiva Europe gosilico chromatography modeling software
    Gosilico Chromatography Modeling Software, supplied by Cytiva Europe, used in various techniques. Bioz Stars score: 94/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/standard+software+package/GoSilico+chromatography+modeling+software+-+Standard+license+package+36+months/pm42834531-109-10-14
    Average 94 stars, based on 2 article reviews
    gosilico chromatography modeling software - by Bioz Stars, 2026-11
    94/100 stars

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    Related Articles

    Software:

    Article Title: Extra-column dead volume in simulated moving bed separations: theory and experiments.
    Article Snippet: In small-scale SMB units typically set up by a number of HPLC columns connected in series, the volume of the connecting tubing parts and valves may become comparable to the column volume.. Therefore, to guarantee proper and satisfying separation results, the introduced extra-column dead volume needs to be considered in the calculations of the operating parameters.. In this work, the impact of extra-column dead eywords: imulated moving bed chromatography xtra-column dead volume hiral chromatography ±)-3,5-Bis[1-(4-methoxyphenyl)-1volume on the separation performance is studied, with the objective to introduce guidelines and rather simple rules to account for it.

    Article Title: Comparative evaluation and simplification of steric mass action and colloidal particle adsorption models for protein ion exchange chromatography
    Article Snippet: Mechanistic modeling of ion exchange chromatography (IEC) has become an essential tool for accelerating process development and deepening mechanistic insight in biopharmaceutical manufacturing.. Although the steric mass action (SMA) model is widely used, it frequently fails to accurately describe elution behavior under high protein loading conditions, whereas the colloidal particle adsorption (CPA) model remains robust.. To clarify the mechanistic advantages of the CPA framework, this study systematically compared the SMA and CPA models for describing the separation of a monoclonal antibody monomer-dimer mixture in IEC.

    Article Title: Development and application of a mechanistic model for protein A resolution of a bispecific antibody for process characterization and optimization.
    Article Snippet: .. Simulations and model quality analysis (Section 3.5) were performed using GoSilico Chromatography Modeling Software (Cytiva) version 1.16.0. ..

    Chromatography:

    Article Title: Comparative evaluation and simplification of steric mass action and colloidal particle adsorption models for protein ion exchange chromatography
    Article Snippet: Mechanistic modeling of ion exchange chromatography (IEC) has become an essential tool for accelerating process development and deepening mechanistic insight in biopharmaceutical manufacturing.. Although the steric mass action (SMA) model is widely used, it frequently fails to accurately describe elution behavior under high protein loading conditions, whereas the colloidal particle adsorption (CPA) model remains robust.. To clarify the mechanistic advantages of the CPA framework, this study systematically compared the SMA and CPA models for describing the separation of a monoclonal antibody monomer-dimer mixture in IEC.

    Article Title: Development and application of a mechanistic model for protein A resolution of a bispecific antibody for process characterization and optimization.
    Article Snippet: .. Simulations and model quality analysis (Section 3.5) were performed using GoSilico Chromatography Modeling Software (Cytiva) version 1.16.0. ..

    Analysis:

    Article Title: Development and application of a mechanistic model for protein A resolution of a bispecific antibody for process characterization and optimization.
    Article Snippet: .. Simulations and model quality analysis (Section 3.5) were performed using GoSilico Chromatography Modeling Software (Cytiva) version 1.16.0. ..



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